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CDC Crossmatch (T cell & B cell) CDC Crossmatch (T cell & B cell) with DTT & AHG Augmentation, Recipient and Donor

Test Name

CDC Crossmatch (T cell & B cell) CDC Crossmatch (T cell & B cell) with DTT & AHG Augmentation, Recipient and Donor

Home Collection, Lab Visit

Test Code

CDCCROSS01

Test Components/ Genes/ Parameters

CDC Crossmatch

Sample Report

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Test Information

TAT DETAILS

Next Day

PRE-TEST INSTRUCTIONS

For Recipient Collect specimen preferably 48 hours after dialysis

CLINICAL UTILITY

This test is utilized to detect preformed antibodies in the serum of the transplant recipient against the donor’s lymphocytes

SPECIMEN STABILITY

Ship at 2-8°C, Do not freeze

METHODOLOGY

Complement Dependent Cytotoxicity with DTT treatment

STORAGE TEMPERATURE

NA

SPECIMEN TYPE

RECIPIENT: 3 mL (2 mL min,) serum from 1 SST, Collect specimen preferably 48 hours after dialysis, DONOR: 12 mL (10 mL min,) whole blood in 2 Yellow Top (ACD) tubes, RECIPIENT : 3mL serum from 1 SST

Frequently Asked Questions

CDC Crossmatch (T cell & B cell) CDC Crossmatch (T cell & B cell) with DTT & AHG Augmentation, Recipient and Donor
This test detects preformed antibodies in the serum of the transplant recipient against the donor’s lymphocytes
NA
The test is done pretransplant to detect the antibodies in recipient serum against the donor
Complement Dependent Cytotoxicity with DTT treatment
No risk
Positive CDC T cell crossmatch reflects presence of donor-specific antibodies (DSA) against MHC class I antigen. Positive B cells cross match reflects the presence of DSA against MHC class I and II antigens.