MGMT promoter methylation analysis
Test Name
MGMT promoter methylation analysis
Home Collection, Lab Visit
Test Code
M0038
Test Components/ Genes/ Parameters
MGMT
Sample Report
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Test Information
TAT DETAILS
10 days
PRE-TEST INSTRUCTIONS
Submit formalin fixed paraffin embedded Tissue Block. Ship at room temperature
CLINICAL UTILITY
Identifying newly diagnosed glioblastomas that may respond to alkylating chemotherapy temozolomide. Guiding therapy decision making for newly diagnosed glioblastomas
SPECIMEN STABILITY
Transport at ambient (18-25°C) temperature
METHODOLOGY
Methylation PCR
STORAGE TEMPERATURE
NA
SPECIMEN TYPE
Surgical tissue/Tissue Block
Frequently Asked Questions
MGMT promoter methylation analysis
Identifying newly diagnosed glioblastomas that may respond to alkylating chemotherapy temozolomide. Guiding therapy decision making for newly diagnosed glioblastomas
The patient should carry the FFPE tissue or block of the Brain Tumor. This process is carried out by Neuro Surgeon in the hospital
The testing is recommended for newly diagnosed glioblastomas. It is important for clinical decision-making of patients to decide temozolomide therapy.
The test is performed by Methylation PCR
There is no risk associated with the test as biopsy will be taken by the trained Neuro surgeon in the hospital under anasthesia
The test result indicates MGMT positive or Negative Tumor. If the promoter gene is methylated, Temozolomide is more effective.