BRCA1 & BRCA2 mutation analysis Somatic NGS
Test Name
BRCA1 & BRCA2 mutation analysis Somatic NGS
Home Collection, Lab Visit
Test Code
B0059a
Test Components/ Genes/ Parameters
BRCA1 & BRCA2
Sample Report
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Test Information
Frequently Asked Questions
BRCA1 & BRCA2 mutation analysis Somatic NGS
This assay detects most of the mutations and insertions/deletions in the BRCA gene which is linked to breast/ovarian cancer. Using the MH guide & Geneyx analysis software, this assay predicts the response of drugs such as PARP inhibitors and helps to tailor the therapy. PARP inhibition results in selective killing of cancer cells which have lost BRCA1 or BRCA2 function.
The patient should carry the FFPE tissue or block of the effected Breast. This process is carried out by Breast Surgeon in the hospital
The test is recommended when there is a family history of Breast & Prostate Cancer
The test is performed with the Next generation sequencing technique
There is no risk associated with the test as biopsy will be taken by the trained surgeon in the hospital under anasthesia
Result is reported as Pathogenic/No pathogenic or likely pathogenic variants causative of the reported phenotype were identified. Correlation with clinical profile and family history is required